Related references
Note: Only part of the references are listed.Clinical Progression in Parkinson Disease and the Neurobiology of Axons
Hsiao-Chun Cheng et al.
ANNALS OF NEUROLOGY (2010)
Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser910/Ser935, disruption of 14-3-3 binding and altered cytoplasmic localization
Nicolas Dzamko et al.
BIOCHEMICAL JOURNAL (2010)
LRRK2 G2019S Mutation Induces Dendrite Degeneration through Mislocalization and Phosphorylation of Tau by Recruiting Autoactivated GSK3β
Chin-Hsien Lin et al.
JOURNAL OF NEUROSCIENCE (2010)
Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease
Byoung Dae Lee et al.
NATURE MEDICINE (2010)
The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease
Mark R. Cookson
NATURE REVIEWS NEUROSCIENCE (2010)
A comparative study of Lrrk2 function in primary neuronal cultures
Justus C. Daechsel et al.
PARKINSONISM & RELATED DISORDERS (2010)
LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model
Javier Alegre-Abarrategui et al.
HUMAN MOLECULAR GENETICS (2009)
Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability - a point of convergence in Parkinsonian neurodegeneration?
Frank Gillardon
JOURNAL OF NEUROCHEMISTRY (2009)
Phosphorylation of Ezrin/Radixin/Moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis
Loukia Parisiadou et al.
JOURNAL OF NEUROSCIENCE (2009)
The Parkinson Disease Protein Leucine-Rich Repeat Kinase 2 Transduces Death Signals via Fas-Associated Protein with Death Domain and Caspase-8 in a Cellular Model of Neurodegeneration
Cherry Cheng-Ying Ho et al.
JOURNAL OF NEUROSCIENCE (2009)
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
Wataru Satake et al.
NATURE GENETICS (2009)
Genome-wide association study reveals genetic risk underlying Parkinson's disease
Javier Simon-Sanchez et al.
NATURE GENETICS (2009)
The WD40 Domain Is Required for LRRK2 Neurotoxicity
Nathan D. Jorgensen et al.
PLOS ONE (2009)
Structure of the Roc-COR domain tandem of C. tepidum, a prokaryotic homologue of the human LRRK2 Parkinson kinase (vol 27, pg 2239, 2008)
Katja Gotthardt et al.
EMBO JOURNAL (2008)
The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation
Elisa Greggio et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells
Edward D. Plowey et al.
JOURNAL OF NEUROCHEMISTRY (2008)
The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules
Payal N. Gandhi et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2008)
Structure of the ROC domain from the Parkinson's disease-associated leucine-rich repeat kinase 2 reveals a dimeric GTPase
Junpeng Deng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
LRRK2 low-penetrance mutations (Gly2019Ser) and risk alleles (Gly2385Arg)-Linking familial and sporadic Parkinson's disease
Vincenzo Bonifati
NEUROCHEMICAL RESEARCH (2007)
LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity
Mahaboobi Jaleel et al.
BIOCHEMICAL JOURNAL (2007)
The familial parkinsonism gene LRRK2 regulates neurite process morphology
David MacLeod et al.
NEURON (2006)
Kinase activity of mutant LRRK2 mediates neuronal toxicity
Wanli W. Smith et al.
NATURE NEUROSCIENCE (2006)
Homotypic FADD interactions through a conserved RXDLL motif are required for death receptor-induced apoptosis
J. R. Muppidi et al.
CELL DEATH AND DIFFERENTIATION (2006)
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin
Elisa Greggio et al.
NEUROBIOLOGY OF DISEASE (2006)
Transform-based backprojection for volume reconstruction of large format electron microscope tilt series
A Lawrence et al.
JOURNAL OF STRUCTURAL BIOLOGY (2006)
Axonal dynactin p150Glued transports caspase-8 to drive retrograde olfactory receptor neuron apoptosis
C Carson et al.
JOURNAL OF NEUROSCIENCE (2005)
Mutations in LRRK2 cause autosomal-dominant Parkinsonism with pleomorphic pathology
A Zimprich et al.
NEURON (2004)
Caspase recruitment domain (CARD)-dependent cytoplasmic filaments mediate bcl10-induced NF-κB activation
C Guiet et al.
JOURNAL OF CELL BIOLOGY (2000)