4.5 Review

Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

Ribonuclease H: the enzymes in eukaryotes

Susana M. Cerritelli et al.

FEBS JOURNAL (2009)

Review Immunology

RNA recognition and signal transduction by RIG-I-like receptors

Mitsutoshi Yoneyama et al.

IMMUNOLOGICAL REVIEWS (2009)

Article Genetics & Heredity

RNaseH2 mutants that cause Aicardi-Goutieres syndrome are active nucleases

Fred W. Perrino et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2009)

Article Multidisciplinary Sciences

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

Teresa Fernandes-Alnemri et al.

NATURE (2009)

Article Multidisciplinary Sciences

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

Veit Hornung et al.

NATURE (2009)

Article Multidisciplinary Sciences

HIN-200 Proteins Regulate Caspase Activation in Response to Foreign Cytoplasmic DNA

Tara L. Roberts et al.

SCIENCE (2009)

Article Biochemistry & Molecular Biology

Trex1 prevents cell-intrinsic initiation of autoimmunity

Daniel B. Stetson et al.

Article Biochemistry & Molecular Biology

The TREX1 Double-stranded DNA Degradation Activity Is Defective in Dominant Mutations Associated with Autoimmune Disease

Duane A. Lehtinen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Multidisciplinary Sciences

Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide

Roberto Lande et al.

NATURE (2007)

Article Genetics & Heredity

Clinical and molecular phenotype of Aicardi-Goutieres syndrome

Gillian Rice et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2007)

Article Multidisciplinary Sciences

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

Akinori Takaoka et al.

NATURE (2007)

Article Biochemistry & Molecular Biology

Fen1 mutations result in autoimmunity, chronic inflammation and cancers

Li Zheng et al.

NATURE MEDICINE (2007)

Article Biochemistry & Molecular Biology

Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW domains

Marina Brucet et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Genetics & Heredity

A mutation in TREX1 that impairs susceptibility to granzyme A-mediated cell death underlies familial chilblain lupus

Min Ae Lee-Kirsch et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2007)

Article Biochemistry & Molecular Biology

The crystal structure of TREX1 explains the 3′ nucleotide specificity and reveals a polyproline II helix for protein partnering

Udesh de Silva et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Genetics & Heredity

Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome

Gillian Rice et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2007)

Article Multidisciplinary Sciences

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates

Andreas Pichlmair et al.

SCIENCE (2006)

Article Genetics & Heredity

Familial chilblain lupus, a monogenic form of cutaneous lupus erythematosus, maps to chromosome 3p

Min Ae Lee-Kirsch et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2006)

Article Medicine, General & Internal

Neonatal-onset multisystem inflammatory disease responsive to interleukin-1β inhibition

Raphaela Goldbach-Mansky et al.

NEW ENGLAND JOURNAL OF MEDICINE (2006)

Article Immunology

Antiviral defense: interferons and beyond

Daniel B. Stetson et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2006)

Article Multidisciplinary Sciences

Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication

Prapaporn Pisitkun et al.

SCIENCE (2006)

Article Biochemistry & Molecular Biology

Shape-specific recognition in the structure of the Vts1p SAM domain with RNA

FC Oberstrass et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)

Article Pediatrics

Genetic syndromes mimic congenital infections

A Sanchis et al.

JOURNAL OF PEDIATRICS (2005)

Article Biochemistry & Molecular Biology

Gene-targeted mice lacking the Trex1 (DNase III) 3′→5′ DNA exonuclease develop inflammatory myocarditis

M Morita et al.

MOLECULAR AND CELLULAR BIOLOGY (2004)

Article Biochemistry & Molecular Biology

RNase H2 of Saccharomyces cerevisiae is a complex of three proteins

HS Jeong et al.

NUCLEIC ACIDS RESEARCH (2004)

Article Genetics & Heredity

Mutation of DNASE1 in people with systemic lupus erythematosus

K Yasutomo et al.

NATURE GENETICS (2001)

Article Biochemistry & Molecular Biology

Structure and expression of the TREX1 and TREX2 3′→5′ exonuclease genes

DJ Mazur et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)