Related references
Note: Only part of the references are listed.Alpha- and gamma-synuclein proteins are present in cerebrospinal fluid and are increased in aged subjects with neurodegenerative and vascular changes
E. B. Mukaetova-Ladinska et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2008)
In vivo alpha-synuclein overexpression in rodents: A useful model of Parkinson's disease?
Marie-Francoise Chesselet
EXPERIMENTAL NEUROLOGY (2008)
Cell systems and the toxic mechanism(s) of alpha-synuclein
Mark R. Cookson et al.
EXPERIMENTAL NEUROLOGY (2008)
Transgenic mice overexpressing tyrosine-to-cysteine mutant human α-synuclein -: A progressive neurodegenerative model of diffuse Lewy body disease
Wenbo Zhou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Retinal ganglion cells downregulate gene expression and lose their Axons within the optic nerve head in a mouse glaucoma model
Ileana Soto et al.
JOURNAL OF NEUROSCIENCE (2008)
Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucoma
Brian P. Buckingham et al.
JOURNAL OF NEUROSCIENCE (2008)
Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression
Paul S. Sharp et al.
NEUROBIOLOGY OF DISEASE (2008)
Modulation of α-Synuclein Expression in Transgenic Animals for Modelling Synucleinopathies - is the Juice Worth the Squeeze?
Vladimir L. Buchman et al.
NEUROTOXICITY RESEARCH (2008)
Disruption of neurofilament network with aggregation of light neurofilament protein: a common pathway leading to motor neuron degeneration due to Charcot-Marie-Tooth disease-linked mutations in NFL and HSPB1
Jinbin Zhai et al.
HUMAN MOLECULAR GENETICS (2007)
Sequence determinants for amyloid fibrillogenesis of human α-synuclein
Shahin Zibaee et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Residual structure, backbone dynamics, and interactions within the synuclein family
Yoon-hui Sung et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
CHIP overexpression reduces mutant androgen receptor protein and ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model
Hiroaki Adachi et al.
JOURNAL OF NEUROSCIENCE (2007)
Age-dependent cognitive decline and amygdala pathology in alpha-synuclein transgenic mice
Christian Freichel et al.
NEUROBIOLOGY OF AGING (2007)
Neuronal intermediate filaments and ALS: A new look at an old question
Shangxi Xiao et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2006)
Transgenic mouse models of amyotrophic lateral sclerosis
Jean-Pierre Julien et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2006)
β-synuclein modulates α-synuclein neurotoxicity by reducing α-synuclein protein expression
Yuxin Fan et al.
HUMAN MOLECULAR GENETICS (2006)
A mutation in the small heat-shock protein HSPB1 leading to distal hereditary motor neuronopathy disrupts neurofilament assembly and the axonal transport of specific cellular cargoes
S Ackerley et al.
HUMAN MOLECULAR GENETICS (2006)
Mechanisms and models of alpha-synuclein-related neurodegeneration
Wolfdieter Springer et al.
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2006)
α-synuclein cooperates with CSPα in preventing neurodegeneration
S Chandra et al.
CELL (2005)
Locomotor activity and evoked dopamine release are reduced in mice overexpressing A30P-mutated human α-synuclein
L Yavich et al.
NEUROBIOLOGY OF DISEASE (2005)
Temporal profiles of neuronal degeneration, glial proliferation, and cell death in hNFL(+/+) and NFL(-/-)mice
JR McLean et al.
GLIA (2005)
Mouse model of multiple system atrophy α-synuclein expression in oligodendrocytes causes glial and neuronal degeneration
I Yazawa et al.
NEURON (2005)
Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina
XQ Mu et al.
DEVELOPMENT (2004)
Accumulation of β- and γ-synucleins in the ubiquitin carboxyl-terminal hydrolase L1-deficient gad mouse
YL Wang et al.
BRAIN RESEARCH (2004)
An antiaggregation gene therapy strategy for Lewy body disease utilizing β-synuclein lentivirus in a transgenic model
M Hashimoto et al.
GENE THERAPY (2004)
Decrease of Hsp25 protein expression precedes degeneration of motoneurons in ALS-SOD1 mice
A Maatkamp et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
Hsp70 reduces α-synuclein aggregation and toxicity
J Klucken et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of γ-synuclein, α-synuclein and double α/γ-synuclein null mutant mice
DC Robertson et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Early and progressive sensorimotor anomalies in mice overexpressing wild-type human α-synuclein
SM Fleming et al.
JOURNAL OF NEUROSCIENCE (2004)
Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy
OV Evgrafov et al.
NATURE GENETICS (2004)
Unraveling the mechanisms involved in motor neuron degeneration in ALS
LI Bruijn et al.
ANNUAL REVIEW OF NEUROSCIENCE (2004)
Phenotypic analysis of neurofilament light gene mutations linked to Charcot-Marie-Tooth disease in cell culture models
R Perez-Olle et al.
HUMAN MOLECULAR GENETICS (2004)
Functions of intermediate filaments in neuronal development and disease
RC Lariviere et al.
JOURNAL OF NEUROBIOLOGY (2004)
Distribution of α- and γ-synucleins in the adult rat brain and their modification by high-dose cocaine treatment
MSB Verca et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2003)
Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence of aggregate formation
S Gispert et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2003)
β-synuclein displays an antiapoptotic p53-dependent phenotype and protects neurons from 6-hydroxydopamine-induced caspase 3 activation -: Cross-talk with α-synuclein and implication for Parkinson's disease
CA da Costa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Ubiquitination of α-synuclein is not required for formation of pathological inclusions in α-synucleinopathies
DM Sampathu et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
Part II:: α-synuclein and its molecular pathophysiological role in neurodegenerative disease
KK Dev et al.
NEUROPHARMACOLOGY (2003)
β-synuclein inhibits formation of α-synuclein protofibrils:: A possible therapeutic strategy against Parkinson's disease
JY Park et al.
BIOCHEMISTRY (2003)
Motor dysfunction and gliosis with preserved dopaminergic markers in human α-synuclein A30P transgenic mice
T Gomez-Isla et al.
NEUROBIOLOGY OF AGING (2003)
Neurons expressing the highest levels of gamma-synuclein are unaffected by targeted inactivation of the gene
N Ninkina et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Effects of Charcot-Marie-Tooth-linked mutations of the neurofilament light subunit on intermediate filament formation
R Perez-Olle et al.
JOURNAL OF CELL SCIENCE (2002)
Development of a new treatment for Alzheimer's disease and Parkinson's disease using anti-aggregatory β-synuclein-derived peptides
M Windisch et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2002)
Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53→Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice
MK Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Differential neuropathological alterations in transgenic mice expressing α-synuclein from the platelet-derived growth factor and Thy-1 promoters
E Rockenstein et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2002)
Neuronal α-synucleinopathy with severe movement disorder in mice expressing A53T human α-synuclein
BI Giasson et al.
NEURON (2002)
Biophysical properties of the synucleins and their propensities to fibrillate -: Inhibition of α-synuclein assembly by β- and γ-synucleins
VN Uversky et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Synucleins in glaucoma:: Implication of γ-synuclein in glaucomatous alterations in the optic nerve
I Surgucheva et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2002)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
KJ Livak et al.
METHODS (2001)
Selective insolubility of α-Synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model
PJ Kahle et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
β-synuclein inhibits α-synuclein aggregation:: A possible role as an anti-parkinsonian factor
M Hashimoto et al.
NEURON (2001)
β-Amyloid peptides enhance α-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease
E Masliah et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Altered expression of the synuclein family mRNA in Lewy body and Alzheimer's disease
E Rockenstein et al.
BRAIN RESEARCH (2001)
Parkinson's disease-associated α-sylnuclein is more fibrillogenic than β- and γ-synuclein and cannot cross-seed its homologs
AL Biere et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Induction of neuronal death by α-synuclein
AR Saha et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2000)
Neurodegeneration with brain iron accumulation, type 1 is characterized by α-, β-, and γ-synuclein neuropathology
JE Galvin et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
A new variant of Charcot-Marie-Tooth disease type 2 is probably the result of a mutation in the neurofilament-light gene
IV Mersiyanova et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2000)
Fiber diffraction of synthetic α-synuclein filaments shows amyloid-like cross-β conformation
LC Serpell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Dopaminergic loss and inclusion body formation in α-synuclein mice:: Implications for neurodegenerative disorders
E Masliah et al.
SCIENCE (2000)
Share Paper
