Related references
Note: Only part of the references are listed.Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex
Ling-Hui Zeng et al.
ANNALS OF NEUROLOGY (2008)
Oligodendrocyte differentiation and implantation: new insights for remyelinating cell therapy
Falak Sher et al.
CURRENT OPINION IN NEUROLOGY (2008)
Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: Effects on mTORC1 and Akt signaling lead to improved survival and function
Lynsey Meikle et al.
JOURNAL OF NEUROSCIENCE (2008)
Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis
John J. Bissler et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Sirolimus (rapamycin): From the soil of Easter Island to a bright future
Kapila V. Paghdal et al.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2007)
Wrapping it up: the cell biology of myelination
Mikael Simons et al.
CURRENT OPINION IN NEUROBIOLOGY (2007)
Characteristics of abnormal diffusivity in normal-appearing white matter investigated with diffusion tensor MR imaging in tuberous sclerosis complex
M. I. Makki et al.
AMERICAN JOURNAL OF NEURORADIOLOGY (2007)
A mouse model of tuberous sclerosis: Neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival
Lynsey Meikle et al.
JOURNAL OF NEUROSCIENCE (2007)
Neocortical hyperexcitability in a human case of tuberous sclerosis complex and mice lacking neuronal expression of TSC1
Yanling Wang et al.
ANNALS OF NEUROLOGY (2007)
Giant cells: Contradiction to two-hit model of tuber formation?
Jaroslaw Jozwiak et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2007)
Generation of a conditional disruption of the Tsc2 gene
Omar Hernandez et al.
GENESIS (2007)
Radial glial cell heterogeneity - The source of diverse progeny in the CNS
Luisa Pinto et al.
PROGRESS IN NEUROBIOLOGY (2007)
The tuberous sclerosis complex
Peter B. Crino et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Molecular genetic determinants of human brain size
Bor Luen Tang
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Rapamycin causes regression of astrocytomas in tuberous sclerosis complex
DN Franz et al.
ANNALS OF NEUROLOGY (2006)
Growing roles for the mTOR pathway
DD Sarbassov et al.
CURRENT OPINION IN CELL BIOLOGY (2005)
A mouse model of tuberous sclerosis 1 showing background specific early post-natal mortality and metastatic renal cell carcinoma
C Wilson et al.
HUMAN MOLECULAR GENETICS (2005)
Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations
MG Butler et al.
JOURNAL OF MEDICAL GENETICS (2005)
Efficacy of a rapamycin analog (CCI-779) and IFN-γ in tuberous sclerosis mouse models
L Lee et al.
GENES CHROMOSOMES & CANCER (2005)
Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex
C Englund et al.
JOURNAL OF NEUROSCIENCE (2005)
Effects of rapamycin in the Eker rat model of tuberous sclerosis complex
H Kenerson et al.
PEDIATRIC RESEARCH (2005)
Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: A major site of neurogenesis
W Haubensak et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases
SC Noctor et al.
NATURE NEUROSCIENCE (2004)
Managing epilepsy in tuberous sclerosis complex
EA Thiele
JOURNAL OF CHILD NEUROLOGY (2004)
Mouse models of tuberous sclerosis complex
DK Scheidenhelm et al.
JOURNAL OF CHILD NEUROLOGY (2004)
Behavioral and cognitive aspects of tuberous sclerosis complex
P Prather et al.
JOURNAL OF CHILD NEUROLOGY (2004)
Brain abnormalities in tuberous sclerosis complex
FJ DiMario
JOURNAL OF CHILD NEUROLOGY (2004)
Molecular pathogenesis of tuber formation in tuberous sclerosis complex
PB Crino
JOURNAL OF CHILD NEUROLOGY (2004)
Fibroblast growth factor receptor 1 is required for the proliferation of hippocampal progenitor cells and for hippocampal growth in mouse
Y Ohkubo et al.
JOURNAL OF NEUROSCIENCE (2004)
Absence of allelic loss in cytomegalic neurons of cortical tuber in the Eker rat model of tuberous sclerosis
M Mizuguchi et al.
ACTA NEUROPATHOLOGICA (2004)
Pathogenesis of tuberous sclerosis subependymal giant cell astrocytornas:: Biallelic inactivation of TSC1 or TSC2 leads to rnTOR activation
JA Chan et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2004)
Expression of Cux-1 and Cux-2 in the subventricular zone and upper layers II-IV of the cerebral cortex
M Nieto et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2004)
Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins
Y Zhang et al.
NATURE CELL BIOLOGY (2003)
Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2
A Garami et al.
MOLECULAR CELL (2003)
Characterization of Foxp2 and Foxp1 mRNA and protein in the developing and mature brain
RJ Ferland et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2003)
GβL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR
DH Kim et al.
MOLECULAR CELL (2003)
Astrocyte-specific TSC1 conditional knockout mice exhibit abnormal neuronal organization and seizures
EJ Uhlmann et al.
ANNALS OF NEUROLOGY (2002)
Hemimegalencephaly in tuberous sclerosis complex
P Galluzzi et al.
JOURNAL OF CHILD NEUROLOGY (2002)
Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling
XS Gao et al.
NATURE CELL BIOLOGY (2002)
MTOR interacts with Raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
DH Kim et al.
CELL (2002)
Regulation of cerebral cortical size by control of cell cycle exit in neural precursors
A Chenn et al.
SCIENCE (2002)
Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-Kinase/Akt pathway
BD Manning et al.
MOLECULAR CELL (2002)
A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells
DJ Kwiatkowski et al.
HUMAN MOLECULAR GENETICS (2002)
hGFAP-cre transgenic mice for manipulation of glial and neuronal function in vivo
L Zhuo et al.
GENESIS (2001)
A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice
T Kobayashi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth
XS Gao et al.
GENES & DEVELOPMENT (2001)
Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size
CJ Potter et al.
CELL (2001)
The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation
N Tapon et al.
CELL (2001)
Neurons derived from radial glial cells establish radial units in neocortex
SC Noctor et al.
NATURE (2001)
Mutational analysis in a cohort of 224 tuberous sclerosis patients indicates increased severity of TSC2, compared with TSC1, disease in multiple organs
SL Dabora et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2001)
The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination
G Benvenuto et al.
ONCOGENE (2000)
Molecular genetic advances in tuberous sclerosis
JP Cheadle et al.
HUMAN GENETICS (2000)