4.5 Article

Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43

Related references

Note: Only part of the references are listed.
Article Clinical Neurology

TARDBP Mutations in Motoneuron Disease with Frontotemporal Lobar Degeneration

Lina Benajiba et al.

ANNALS OF NEUROLOGY (2009)

Article Biochemistry & Molecular Biology

Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies

Lionel M. Igaz et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Multidisciplinary Sciences

Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity

Yong-Jie Zhang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Clinical Neurology

TDP-43 mutation in familial amyotrophic lateral sclerosis

Akio Yokoseki et al.

ANNALS OF NEUROLOGY (2008)

Article Clinical Neurology

TDP-43 A315T mutation in familial motor neuron disease

Michael A. Gitcho et al.

ANNALS OF NEUROLOGY (2008)

Article Clinical Neurology

Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Masato Hasegawa et al.

ANNALS OF NEUROLOGY (2008)

Article Biochemistry & Molecular Biology

Abnormal phosphorylation of ser409/410 of TDP-43 in FTLD-U and ALS

Yuki Inukai et al.

FEBS LETTERS (2008)

Article Cell Biology

Structural determinants of the cellular localization and shuttling of TDP-43

Youhna M. Ayala et al.

JOURNAL OF CELL SCIENCE (2008)

Article Genetics & Heredity

TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis

Edor Kabashi et al.

NATURE GENETICS (2008)

Article Multidisciplinary Sciences

A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDR-43 aggregation and cellular toxicity

Brian S. Johnson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

Jemeen Sreedharan et al.

SCIENCE (2008)

Article Neurosciences

Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43

Yong-Jie Zhang et al.

JOURNAL OF NEUROSCIENCE (2007)

Article Biochemistry & Molecular Biology

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Tetsuaki Arai et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)

Article Multidisciplinary Sciences

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Manuela Neumann et al.

SCIENCE (2006)

Article Biochemistry & Molecular Biology

Human, Drosophila, and C-elegans TDP43:: Nucleic acid binding properties and splicing regulatory function

YM Ayala et al.

JOURNAL OF MOLECULAR BIOLOGY (2005)

Article Biotechnology & Applied Microbiology

Structural diversity and functional implications of the eukaryotic TDP gene family

HY Wang et al.

GENOMICS (2004)

Article Psychiatry

Frontotemporal dementia

JS Snowden et al.

BRITISH JOURNAL OF PSYCHIATRY (2002)

Article Biochemistry & Molecular Biology

Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping

E Buratti et al.

EMBO JOURNAL (2001)

Article Biochemistry & Molecular Biology

Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening

Y Nagai et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)