4.2 Article

Three novel alleles at the HLA-DRB1 locus identified by sequence-based typing

Journal

HUMAN IMMUNOLOGY
Volume 73, Issue 1, Pages 67-69

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.humimm.2011.11.004

Keywords

HLA-DRB1*03:05:03; HLA-DRB1*11:10:02; HLA-DRB1*14:86; SBT

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We describe here the sequences of 3 new HLA-DRB1 variants officially named DRB1*03:05:03, DRB1*11:10:02, and DRB1*14:86. These novel alleles have been detected in 3 Caucasoid individuals by sequence-based typing. The first and second alleles are the result of a silent mutation, which does not imply any amino acid change. The sequence of DRB1*14:86 exhibits a single nucleotide difference with the allele DRB1*14:01:01 at position 239. (C) 2012 American Society for Histocompatibility and Immunogenetics. Published by Elsevier Inc. All rights reserved.

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