Journal
HUMAN BRAIN MAPPING
Volume 34, Issue 11, Pages 3055-3065Publisher
WILEY
DOI: 10.1002/hbm.22127
Keywords
dyslexia; reading; magnetic resonance imaging; meta-analysis; cerebral cortex
Funding
- Austrian Science Foundation [P18832-B02]
- European Union
- Austrian Science Fund (FWF) [P18832] Funding Source: Austrian Science Fund (FWF)
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We used coordinate-based meta-analysis in order to objectively quantify gray matter abnormalities reported in nine Voxel-Based Morphometry studies of developmental dyslexia. Consistently across studies, reduced gray matter volume in dyslexic readers was found in the right superior temporal gyrus and left superior temporal sulcus. These results were related to findings from previous meta-analyses on functional brain abnormalities in dyslexic readers. Convergence of gray matter reduction and reading-related underactivation was found for the left superior temporal sulcus. Recent studies point to the presence of both functional and structural abnormalities in left temporal and occipito-temporal brain regions before reading onset. Hum Brain Mapp 34:3055-3065, 2013. (c) 2012 Wiley Periodicals, Inc.
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