Journal
HUMAN & EXPERIMENTAL TOXICOLOGY
Volume 30, Issue 12, Pages 2027-2030Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/0960327111408153
Keywords
polyphenols; hormesis; quercetin; low doses
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Hormesis is a dose response phenomenon, usually present in plants and animals, characterized by a low-dose stimulation and high-dose inhibition, often resulting in typical U-shaped or J-shaped curves. Hormesis has become an interesting model for toxicology and risk assessment, as it has been described for several nature-derived phytochemicals but also because this adaptive response to stressors might hide an underlying more general behaviour of cell towards low doses.
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