Journal
HUMAN & EXPERIMENTAL TOXICOLOGY
Volume 30, Issue 8, Pages 870-875Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/0960327110382131
Keywords
Dendropanax morbifera; araliaceae; antidiabetic; streptozotocin-induced; dendropanoxide
Categories
Ask authors/readers for more resources
The present study evaluated the antidiabetic effect of Dendropanoxide (DP) from Dendropanax morbifera Leveille in normal and streptozotocin-induced diabetic rats. DP in the streptozotocin-induced diabetic rats showed significant hypoglycemic activity for 14 days significantly decreased the serum glucose, total cholesterol, triglycerides, urea, uric acid, creatinine, aspartate amino transferase (AST) and alanine amino transferase (ALT) while it increased the serum insulin in diabetic rats but not in normal rats (p < 0.05; at doses of 30, 60 and 100 mg/kg for 14 days). A comparison was made between the action of DP and glibenclamide (600 mg/kg), a known antidiabetic drug. The antidiabetic effect of the DP was more effective than that observed with glibenclamide.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available