Journal
HUMAN & EXPERIMENTAL TOXICOLOGY
Volume 28, Issue 6-7, Pages 393-400Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/0960327109105161
Keywords
nanomaterial; molecular biology; toxicology
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Funding
- NIEHS NIH HHS [K99 ES015426] Funding Source: Medline
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There is an urgent need to develop efficient and rapid strategies in order to characterize the potential health risks associated with nanomaterials, given the speed with which applications and uses are increasing. Use of standard toxicity methods will not be sufficient to meet this need. This article proposes the adoption of two novel guidances: the system's biological approach to toxicity testing advocated by the US National Research Council and a nanobiological perspective that identifies key events at the nanoscale that are relevant to signal transduction and structural biology.
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