Journal
HUMAN & EXPERIMENTAL TOXICOLOGY
Volume 27, Issue 8, Pages 621-625Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/0960327108098488
Keywords
bioevidential scrutiny; evidence-based policy; hormetic effects; severe testing; statistical inference; statistical vs. substantive significance; risk evidence
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Ethical issues of evidence relevant for risk policy are not adequately addressed if divorced from issues of the responsible interpretation of the risk evidence itself. Evidence for hormetic hypotheses are based on data that disagree with a null hypothesis asserting H0: zero (0) improvement (at low doses). We critically evaluate some of the reasoning and the procedures used by leading proponents of hormesis, and suggest how potential errors may be avoided.
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