Journal
HORMONE RESEARCH IN PAEDIATRICS
Volume 75, Issue 5, Pages 322-328Publisher
KARGER
DOI: 10.1159/000326684
Keywords
Endocrinology; Genetics; Genome-wide association studies; Pediatrics
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Genome-wide association (GWA) studies are a powerful tool for understanding the genetic underpinnings of human disease. In this article, we briefly review the role and findings of GWA studies in type 1 diabetes, stature, pubertal timing, obesity, and vitamin D deficiency. We then discuss the present and future implications of these findings with regards to disease prediction, uncovering basic biology, and the development of novel therapeutic agents. Copyright (c) 2011 S. Karger AG, Basel
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