Journal
HIV MEDICINE
Volume 13, Issue 9, Pages 526-532Publisher
WILEY-BLACKWELL
DOI: 10.1111/j.1468-1293.2012.01003.x
Keywords
albuminuria; HIV infection; proteinuria; urine albumin; creatinine ratio; urine protein; creatinine ratio
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Funding
- Boehringer Ingelheim
- Bristol Myers Squib
- Gilead
- Merck Sharp and Dohme
- Tibotec
- Viiv Healthcare
- Bristol Myers Squibb
- Gilead Sciences
- Janssen-Cilag
- Abbott
- Janssen
- Merck
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Objective We recently showed that a urine albumin/total protein ratio (uAPR)??30?mg/mmol) into two groups: those with predominantly tubular proteinuria (TP) (uAPR??100?mg/mmol), a renal assessment was made; eight had a kidney biopsy. In all cases, the uAPR results correlated with the nephrological diagnosis. Conclusions In HIV-infected patients, measuring uAPR may help to identify patients in whom a renal biopsy is indicated, and those in whom tubular dysfunction might be an important cause of proteinuria and which may be related to antiretroviral toxicity. We suggest that this would be useful as a routine screening procedure in patients with proteinuria.
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