Journal
HISTOPATHOLOGY
Volume 64, Issue 1, Pages 2-11Publisher
WILEY
DOI: 10.1111/his.12267
Keywords
sarcoma; soft tissue; tumour; WHO
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The new World Health Organization (WHO) classification of soft tissue tumours was published in early 2013, almost 11years after the previous edition. While the number of newly recognized entities included for the first time is fewer than that in 2002, there have instead been substantial steps forward in molecular genetic and cytogenetic characterization of this family of tumours, leading to more reproducible diagnosis, a more meaningful classification scheme and providing new insights regarding pathogenesis, which previously has been obscure in most of these lesions. This brief overview summarizes changes in the classification in each of the broad categories of soft tissue tumour (adipocytic, fibroblastic, etc.) and also provides a short summary of newer genetic data which have been incorporated in the WHO classification.
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