4.6 Review

Clues to the diagnosis of atypical melanocytic lesions

Journal

HISTOPATHOLOGY
Volume 56, Issue 1, Pages 100-111

Publisher

WILEY-BLACKWELL PUBLISHING, INC
DOI: 10.1111/j.1365-2559.2009.03451.x

Keywords

atypical acral naevus; atypical genital naevus; balloon cell melanoma; clear cell melanoma; desmoplastic melanoma; melanoma with heterologous differentiation; neonatal naevus; naevoid melanoma; proliferation nodule; recurrent and traumatized naevus; rhabdoid melanoma; signet-ring cell melanoma

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This review, based on a lecture given at the 2009 Update in Dermatopathology meeting held at the Institute of Dermatology (London, UK), discusses the problem of misdiagnosing atypical benign melanocytic lesions as melanoma and the alternative problem of interpreting naevoid melanoma as a banal naevus. Consequences are considered. Brief consideration of a range of other melanoma variants that may be a source of diagnostic difficulty is also included.

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