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Lipid droplets: a classic organelle with new outfits

Journal

HISTOCHEMISTRY AND CELL BIOLOGY
Volume 130, Issue 2, Pages 263-279

Publisher

SPRINGER
DOI: 10.1007/s00418-008-0449-0

Keywords

lipid droplet; lipid ester; phospholipid; cholesterol; PAT protein; caveolin

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Lipid droplets are depots of neutral lipids that exist virtually in any kind of cell. Recent studies have revealed that the lipid droplet is not a mere lipid blob, but a major contributor not only to lipid homeostasis but also to diverse cellular functions. Because of the unique structure as well as the functional importance in relation to obesity, steatosis, and other prevailing diseases, the lipid droplet is now reborn as a brand new organelle, attracting interests from researchers of many disciplines.

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