Journal
HIGH PRESSURE RESEARCH
Volume 32, Issue 1, Pages 97-102Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/08957959.2011.642376
Keywords
high pressure equipment; neutron scattering; molecular dynamics; biomolecules
Categories
Ask authors/readers for more resources
The design of new high pressure equipment for structural and dynamical studies on samples in solution is described. We present two sample cells for applying pressures up to 150 and 700 MPa (i.e. 1.5 and 7 kbar), respectively. These cells are mounted on special sticks and inserted into the calorimeter of a cryostat to regulate the temperature. Different parts of the equipment - the pressure controller, the sticks and the cells - are described. In addition, radiography tests which were performed with neutrons in situ at the Institut Laue Langevin to verify the tightness of the cells and the hydrostatic transmission of the pressure to the sample are presented. First results on model lipids are in agreement with former results by R. Winter et al. [Towards an understanding of the temperature/pressure configurational and free-energy landscape of biomolecules, J. Non-Equilib. Thermodyn. 32 (2007), pp. 41-97].
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available