Acute Effects of Normobaric Hypoxia on Hand-Temperature Responses During and After Local Cold Stress

The purpose was to investigate acute effects of normobaric hypoxia on hand-temperature responses during and after a cold-water hand immersion test. Fifteen males performed two right-hand immersion tests in 8 degrees C water, during which they were inspiring either room air (Fio(2): 0.21; AIR), or a hypoxic gas mixture (Fio(2): 0.14; HYPO). The tests were conducted in a counterbalanced order and separated by a 1-hour interval. Throughout the 30-min cold-water immersion (CWI) and the 15-min spontaneous rewarming (RW) phases, finger-skin temperatures were measured continuously with thermocouple probes; infrared thermography was also employed during the RW phase to map all segments of the hand. During the CWI phase, the average skin temperature (Tavg) of the fingers did not differ between the conditions (AIR: 10.2 +/- 0.5 degrees C, HYPO: 10.0 +/- 0.5 degrees C; p = 0.67). However, Tavg was lower in the HYPO than the AIR RW phase (AIR: 24.5 +/- 3.4 degrees C; HYPO: 22.0 +/- 3.8 degrees C; p = 0.002); a response that was alike in all regions of the immersed hand. Accordingly, present findings suggest that acute exposure to normobaric hypoxia does not aggravate the cold-induced drop in hand temperature of normothermic males. Still, hypoxia markedly impairs the rewarming responses of the hand.