4.2 Article

TWO NEW FUROFURAN LIGNANS FROM KANDELIA OBOVATA

Journal

HETEROCYCLES
Volume 87, Issue 5, Pages 1093-1098

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/COM-13-12688

Keywords

Furofuran Lignan; Kandelia obovata

Funding

  1. Planned Science and Technology Project of Wenzhou [Y20080115]
  2. Wenzhou Medical College Science Foundation [QTJ06003]
  3. NSFC [41176149]

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Two new furofuran lignans, named kandelisesquilignan A and kandelisesquilignan B, were isolated from the aerial part of Kandelia obovata, together with seven known compounds beta-sitosterol, betulinic acid, daucosterol, friedelin, lupeol, apigenin and acacetin. Their structures were characterized on the basis of spectral data. The two new compounds showed significant antioxidant activity by the DPPH method (IC50 = 31.9 and 27.8 mu g/mL).

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