Related references
Note: Only part of the references are listed.Syntheses and biological activities of KRN7000 analogues having aromatic residues in the acyl and backbone chains with varying stereochemistry
Jeong-Ju Park et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Synthesis and biological activity of ester and ether analogues of α-galactosylceramide (KRN7000)
Masao Shiozaki et al.
CARBOHYDRATE RESEARCH (2010)
Rational Design and Evaluation of a Branched-Chain-Containing Glycolipid Antigen That Binds to CD1d
Dong Jae Baek et al.
CHEMISTRY-AN ASIAN JOURNAL (2010)
Induction of T(h)1-biased cytokine production by alpha-carba-GalCer, a neoglycolipid ligand for NKT cells
Takuya Tashiro et al.
INTERNATIONAL IMMUNOLOGY (2010)
Mechanisms for Glycolipid Antigen-Driven Cytokine Polarization by V alpha 14i NKT Cells
Barbara A. Sullivan et al.
JOURNAL OF IMMUNOLOGY (2010)
Synthesis of phalluside-1 and Sch II using 1,2-metallate rearrangements
Fiona J. Black et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2010)
A general and concise asymmetric synthesis of sphingosine, safingol and phytosphingosines via tethered aminohydroxylation (Publication with Expression of Concern. See vol. 15, pg. 5851, 2017)
Pradeep Kumar et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2010)
Synthesis and Evaluation of Amino-Modified α-GalCer Analogues
Matthias Trappeniers et al.
ORGANIC LETTERS (2010)
RCAI-37, 56, 59, 60, 92, 101, and 102, cyclitol and carbasugar analogs of KRN7000: Their synthesis and bioactivity for mouse lymphocytes to produce Th1-biased cytokines
Takuya Tashiro et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
Synthesis and evaluation of 3- and 4-deoxy and -fluoro analogs of the immunostimulatory glycolipid, KRN7000
Ravinder Raju et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
The Roles of 3′ and 4′ Hydroxy Groups in α-Galactosylceramide Stimulation of Invariant Natural Killer T Cells
Chengfeng Xia et al.
CHEMMEDCHEM (2009)
Aminocyclitol-Substituted Phytoceramides and their Effects on iNKT Cell Stimulation
Youssef Harrak et al.
CHEMMEDCHEM (2009)
Nonglycosidic Agonists of Invariant NKT Cells for Use as Vaccine Adjuvants
B. Gopal Reddy et al.
CHEMMEDCHEM (2009)
The Synthesis and in vivo Evaluation of 2′,2′-Difluoro KRN7000
Leo Leung et al.
CHEMMEDCHEM (2009)
Carbohydrate specificity of the recognition of diverse glycolipids by natural killer T cells
Dirk M. Zajonc et al.
IMMUNOLOGICAL REVIEWS (2009)
Identification of C-glycoside analogues that display a potent biological activity against murine and human invariant natural killer T cells
Xiangming Li et al.
IMMUNOLOGY (2009)
Focus on the Controversial Activation of Human iNKT Cells by 4-Deoxy Analogue of KRN7000
Vivien Lacone et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Structural Evaluation of Potent NKT Cell Agonists: Implications for Design of Novel Stimulatory Ligands
Andre Schiefner et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
An Efficient and General Enantioselective Synthesis of Sphingosine, Phythosphingosine, and 4-Substituted Derivatives
Josep Llaveria et al.
ORGANIC LETTERS (2009)
Glycolipids as immunostimulating agents
Douglass Wu et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
RCAI-8, 9, 18, 19, and 49-52, conformationally restricted analogues of KRN7000 with an azetidine or a pyrrolidine ring: Their synthesis and bioactivity for mouse natural killer T cells to produce cytokines
Ken-ichi Fuhshuku et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
RCAI-17, 22, 24-26, 29, 31, 34-36, 38-40, and 88, the analogs of KRN7000 with a sulfonamide linkage: Their synthesis and bioactivity for mouse natural killer T cells to produce Th2-biased cytokines
Takuya Tashiro et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
Synthesis of all stereoisomers of KRN7000, the CD1d-binding NKT cell ligand
Jeong-Ju Park et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
α-S-GalCer: Synthesis and evaluation for iNKT cell stimulation
Marisa L. Blauvelt et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Synthesis and in vitro evaluation of α-GalCer epimers
Matthias Trappeniers et al.
CHEMMEDCHEM (2008)
Crystal structures of mouse CD1d-iGb3 complex and its cognate vα14 T cell receptor suggest a model for dual recognition of foreign and self glycolipids
Dirk M. Zajonc et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
6′-Derivatised α-GalCer Analogues Capable of Inducing Strong CD1d-Mediated Th1-Biased NKT Cell Responses in Mice
Matthias Trappeniers et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Quantitative microarray analysis of intact glycolipid - CD1d interaction and correlation with cell-based cytokine production
Pi-Hui Liang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Synthesis and In Vivo Evaluation of 4-Deoxy-4,4-difluoro-KRN7000
Leo Leung et al.
ORGANIC LETTERS (2008)
The First Synthesis of a Thioglycoside Analogue of the Immunostimulant KRN7000
Ravindra T. Dere et al.
ORGANIC LETTERS (2008)
RCAI-61, the 6′-O-methylated analog of KRN7000: its synthesis and potent bioactivity for mouse lymphocytes to produce interferon-γ in vivo
Takuya Tashiro et al.
TETRAHEDRON LETTERS (2008)
Recent advances in the glycosylation of sphingosines and ceramides
Jose Antonio Morales-Serna et al.
CARBOHYDRATE RESEARCH (2007)
Synthesis and evaluation of human T cell stimulating activity of an α-sulfatide analogue
Laura Franchini et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2007)
CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor
Natalie A. Borg et al.
NATURE (2007)
Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids
Ya-Jen Chang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Minimum structure requirement of immunomodulatory glycolipids for predominant Th2 cytokine induction and the discovery of non-linear phytosphingosine analogs
Tetsuya Toba et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
RCAI-56, a carbocyclic analogue of KRN7000:: its synthesis and potent activity for natural killer (NK) T cells to preferentially produce interferon-γ
Takuya Tashiro et al.
TETRAHEDRON LETTERS (2007)
Development of highly potent chiral discrimination methods that solve the problems of the diastereomer method
Hiroshi Ohrui et al.
PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES (2007)
Normal development and function of invariant natural killer T cells in mice with isoglobotrihexosylceramide (iGb3) deficiency
Stefan Porubsky et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Synthesis and evaluation of 1,2,3-triazole containing analogues of the immunostimulant α-GalCer
Taeho Lee et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
Highly efficient stereoselective synthesis of D-erythro-sphingosine and D-lyxo-phytosphingosine
Giuliana Righi et al.
TETRAHEDRON (2006)
Versatile synthetic method for sphingolipids and functionalized sphingosine derivatives via olefin cross metathesis
Tetsuya Yamamoto et al.
ORGANIC LETTERS (2006)
Synthesis and evaluation of an α-C-Galactosylceramide analogue that induces Th1-biased responses in human natural killer T cells
Xuequan Lu et al.
CHEMBIOCHEM (2006)
Efficient synthesis of D-erythro-sphingosine and D-erythro-azidosphingosine from D-ribo-phytosphingosine via a cyclic sulfate intermediate
Sanghee Kim et al.
JOURNAL OF ORGANIC CHEMISTRY (2006)
α-C-galactosylceramides:: Synthesis and immunology
Richard W. Franck et al.
ACCOUNTS OF CHEMICAL RESEARCH (2006)
Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria
Yuki Kinjo et al.
NATURE IMMUNOLOGY (2006)
An efficient high-yield synthesis of D-ribo-phytosphingosine
Marco Lombardo et al.
ORGANIC LETTERS (2006)
Structure-based discovery of glycolipids for CD1d-mediated NKT cell activation: Tuning the adjuvant versus immunosuppression activity
Masakazu Fujio et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)
A modified α-galactosyl ceramide for staining and stimulating natural killer T cells
Yang Liu et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2006)
Glycolipids for natural killer T cells
Paul B. Savage et al.
CHEMICAL SOCIETY REVIEWS (2006)
An efficient synthesis of D-erythro- and D-threo-sphingosine from D-glucose:: Olefin cross-metathesis approach
VD Chaudhari et al.
ORGANIC LETTERS (2005)
Synthesis and evaluation of sphinganine analogues of KRN7000 and OCH
RM Ndonye et al.
JOURNAL OF ORGANIC CHEMISTRY (2005)
Synthesis of sphinosine relatives. Part 27. Synthesis and absolute configuration of 6-hydroxylated new ceramides in human skin, ceramides B, 4, 7 and 8
Y Masuda et al.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2005)
Synthesis of the glycosphingolipid β-galactosyl ceramide and analogues via olefin cross metathesis
AN Rai et al.
JOURNAL OF ORGANIC CHEMISTRY (2005)
The crystal structure of human CD1d with and without α-galactosylceramide
M Koch et al.
NATURE IMMUNOLOGY (2005)
Immunomodulatory α-galactoglycosphingolipids:: Synthesis of 2′-fluoro-2′-deoxy-α-galactosylceramide and an evaluation of its immunostimulating properties
L Barbieri et al.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2005)
Synthesis and human NKT cell stimulating properties of 3-O-sulfo-α/β-galactosylceramides
GW Xing et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2005)
Recognition of bacterial glycosphingolipids by natural killer T cells
Y Kinjo et al.
NATURE (2005)
Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
J Mattner et al.
NATURE (2005)
Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of α-galactosylceram ides
KOA Yu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Synthesis of α-galactosyl ceramide and the related glycolipids for evaluation of their activities on mouse splenocytes
GT Fan et al.
TETRAHEDRON (2005)
Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells
D Wu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Loading of the antigen-presenting protein CD1d with synthetic glycolipids
FK Wallner et al.
CHEMBIOCHEM (2004)
Immunomodulatory α-galactoglycosphingolipids:: Synthesis of a 2′-O-methyl-α-Gal-GSL and evaluation of its immunostimulating capacity
L Barbieri et al.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2004)
Oxazine formation by MsCl/Et3N as a convenient tool for the stereochemical interconversion of the hydroxyl group in N-acetyl 1,3-aminoalcohols.: Asymmetric synthesis of N-acetyl L-xylo- and L-arabino-phytosphingosines
OV Singh et al.
TETRAHEDRON LETTERS (2004)
Sphingolipid synthesis via olefin cross metathesis:: Preparation of a differentially protected building block and application to the synthesis of D-erythro-ceramide
AN Rai et al.
ORGANIC LETTERS (2004)
Approaches to the preparation of sphinganines
AR Howell et al.
TETRAHEDRON (2004)
Lysosomal glycosphingolipid recognition by NKT cells
DP Zhou et al.
SCIENCE (2004)
A practical synthesis of D-erythro-sphingosine using a cross-metathesis approach
S Torssell et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2004)
The C-glycoside analogue of the immunostimulant alpha-galactosylceramide (KRN7000): Synthesis and striking enhancement of activity
GL Yang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)
Efficient synthesis of α-C-galactosyl ceramide immunostimulants:: Use of ethylene-promoted olefin cross-metathesis
GW Chen et al.
ORGANIC LETTERS (2004)
Effects of lipid chain lengths in α-galactosylceramides on cytokine release by natural killer T cells
RD Goff et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Synthesis and stereochemistry of ceramide B, (2S,3R,4E,6R)-N-(30-hydroxytriacontanoyl)-6-hydroxy-4-sphingenine, a new ceramide in human epidermis
K Mori et al.
TETRAHEDRON LETTERS (2003)
The cerebrosides
RX Tan et al.
NATURAL PRODUCT REPORTS (2003)
Bioorganic chemistry of ceramide
S Brodesser et al.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2003)
Integrative transformation system for the metabolic engineering of the sphingoid base-producing yeast Pichia ciferrii
JH Bae et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2003)
Superior protection against malaria and melanoma metastases by a C-glycoside analogue of the natural killer T cell ligand alpha-galactosylceramide
J Schmieg et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Synthesis of (2S,2′ R,3S,4R)-2-(2′-hydroxy-21′-methyldocosanoylamino)-1,3,4-pentadecanetriol, the ceramide sex pheromone of the female hair crab, Erimacrus isenbeckii
Y Masuda et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2002)
Determination of the absolute configuration at the two cyclopropane moieties of plakoside A, an immunosuppressive marine galactosphingolipid
K Mori et al.
TETRAHEDRON LETTERS (2002)
Immunomodulating glycosphingolipids:: an efficient synthesis of a 2′-deoxy-α-galactosyl-GSL
V Costantino et al.
TETRAHEDRON (2002)
A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells
K Miyamoto et al.
NATURE (2001)
Garner's aldehyde
YF Liang et al.
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 (2001)
Crucial amino acid residues of mouse CD1d for glycolipid ligand presentation to Vα14NKT cells
N Kamada et al.
INTERNATIONAL IMMUNOLOGY (2001)
Epidermosides - Structure and function of skin-specific glycolipids
S Hamanaka et al.
PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES (2001)
Synthesis of (2S,3R,11S,12R,2′R,11′S,12′R)-plakoside A, a prenylated and immunosuppressive marine galactosphingolipid with cyclopropane-containing alkyl chains
M Seki et al.
TETRAHEDRON LETTERS (2001)