Journal
HETEROCYCLES
Volume 83, Issue 9, Pages 2149-2155Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/COM-11-12251
Keywords
HL-60; Antiproliferative Activity; Structure-Activity Relationship
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Funding
- Kagoshima Science Scholarship Foundation
- JSPS [22510236]
- Grants-in-Aid for Scientific Research [20310137, 22510236] Funding Source: KAKEN
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Five new eunicellin-type diterpenes were isolated from the soft coral Litophyton viscudium. The structures of the compounds were elucidated mainly on the basis of extensive spectroscopic analysis. Compounds exhibited cytotoxic activity against HL-60 with IC50 values of 4.2-50 mu M.
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