4.2 Article

REUSABLE POLYMER-SUPPORTED TERPYRIDINE COPPER COMPLEX FOR [3+2] HUISGEN CYCLOADDITION IN WATER

Journal

HETEROCYCLES
Volume 81, Issue 3, Pages 601-610

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/COM-09-11872

Keywords

Copper; Terpyridine; Click Chemistry; Triazole; Azide

Funding

  1. University of the Ryukyus
  2. Joint Study in Cooperative Research Center

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A polymer-supported terpyridine copper(I) complex was prepared and found to promote the Huisgen [3+2] cycloaddition reaction between azides and alkynes in water to give the corresponding triazoles with up to 87% isolated yield. This catalyst was recovered and reused several times without any loss in catalytic activity.

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