Journal
HETEROCYCLES
Volume 81, Issue 2, Pages 293-304Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/COM-09-11850
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Funding
- Seoul R BD Program [10541]
- Yonsung Fine Chemicals Co., Ltd
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Ail efficient procedure was developed to synthesize oxazoline as key intermediate in the total synthesis of (+)-lactacystin using palladium(0)-catalyzed intramolecular cyclization of isopentenyl benzamide via a pi-allylpalladium complex. A convenient and efficient method was developed for the synthesis of the optically pure alpha-amino-beta-hydroxy acid.
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