Journal
HETEROCYCLES
Volume 78, Issue 6, Pages 1445-1452Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/COM-08-11569
Keywords
3,4-Diaminoglyoxime; Benzaldehyde; p-Toluenesulfonic Acid; (Z)-4-Amino-5-hydroxyimino-2,5-dihydro-1H-imidazole 3-Oxide Nitrone
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Highly functionalized derivatives of (7-)-4-amino-5-(hydroxyimino)2,5-dihydro-1H-imidazole 3-oxide were first and conveniently synthesized by the reactions of 3,4-diaminoglyoxime with benzaldehyde derivatives in the presence of p-toluenesulfonic acid. The procedure represents an effective method to obtain a new kind of nitrones.
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