Journal
HETEROCYCLES
Volume 78, Issue 3, Pages 757-761Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/COM-08-11533
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Funding
- national key technology RD program [2006BAE02BO4]
- development program of China [2006AA020101]
- Post-doctoral Science Fund of China [20070420980]
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A series of 5-arylidenethiazolidine-2,4-diones was synthesized by the Knoevenagel condensation of thiazolidine-2,4-dione with aromatic aldehydes with alkaline ionic liquid 1-butyl-3-methylimidazolium hydroxide ([bmim]OH) as dual solvent and catalyst. This method provides many advantages such as being environmentally benign, simple work-up, short reaction times, obtaining in good to excellent yields, and the reusability of ionic liquid.
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