Journal
HEPATOLOGY INTERNATIONAL
Volume 7, Issue 4, Pages 951-958Publisher
SPRINGER
DOI: 10.1007/s12072-013-9475-7
Keywords
Human hepatocytes; Liver cell isolation; Parenchymal liver cells; Non-parenchymal liver cells; Liver cell culture
Categories
Funding
- [BMBF-0315741]
- [BMBF-0316058A]
- [BMBF-0315753]
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Many reports describing parenchymal liver cell isolation have been published so far. However, recent evidence has clearly demonstrated that non-parenchymal liver cells play an important role in many pathophysiologies of the liver, such as drug-induced liver diseases, inflammation, and the development of liver fibrosis and cirrhosis. In this study, we present an overview of the current methods for isolating and characterizing parenchymal and non-parenchymal liver cells.
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