Related references
Note: Only part of the references are listed.Is Toxicogenomics a More Reliable and Sensitive Biomarker than Conventional Indicators from Rats To Predict Drug-Induced Liver Injury in Humans?
Min Zhang et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2012)
A Decade of Toxicogenomic Research and Its Contribution to Toxicological Science
Minjun Chen et al.
TOXICOLOGICAL SCIENCES (2012)
FDA-approved drug labeling for the study of drug-induced liver injury
Minjun Chen et al.
DRUG DISCOVERY TODAY (2011)
Developing Structure-Activity Relationships for the Prediction of Hepatotoxicity
Nigel Greene et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2010)
Lipophilicity in drug discovery
Michael J. Waring
EXPERT OPINION ON DRUG DISCOVERY (2010)
Back to basics for idiosyncratic drug-induced liver injury: Dose and metabolism make the poison
F. Ballet
GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE (2010)
Risk Factors for Idiosyncratic Drug-Induced Liver Injury
Naga Chalasani et al.
GASTROENTEROLOGY (2010)
Oral Medications with Significant Hepatic Metabolism at Higher Risk for Hepatic Adverse Events
Craig Lammert et al.
HEPATOLOGY (2010)
Defining optimum lipophilicity and molecular weight ranges for drug candidates-Molecular weight dependent lower logD limits based on permeability
Michael J. Waring
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Pharmacological Promiscuity: Dependence on Compound Properties and Target Specificity in a Set of Recent Roche Compounds
Jens-Uwe Peters et al.
CHEMMEDCHEM (2009)
Physicochemical drug properties associated with in vivo toxicological outcomes: a review
David A. Price et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2009)
Trovafloxacin: a case study of idiosyncratic or iatrogenic liver toxicity - molecular mechanisms and lessons for pharmacotoxicity
J. Borlak
HUMAN & EXPERIMENTAL TOXICOLOGY (2009)
The Liver Toxicity Biomarker Study: Phase I Design and Preliminary Results
Robert N. McBurney et al.
TOXICOLOGIC PATHOLOGY (2009)
Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies
Laura K. Schnackenberg et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2009)
Physiochemical drug properties associated with in vivo toxicological outcomes
Jason D. Hughes et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
The role of early in vivo toxicity testing in drug discovery toxicology
Mark R. Fieldent et al.
EXPERT OPINION ON DRUG SAFETY (2008)
Relationship between daily dose of oral medications and idiosyncratic drug-induced liver injury: Search for signals
Craig Lammert et al.
HEPATOLOGY (2008)
Mechanisms of trovafloxacin hepatotoxicity: Studies of a model cyclopropylamine-containing system
Qin Sun et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
The influence of drug-like concepts on decision-making in medicinal chemistry
Paul D. Leeson et al.
NATURE REVIEWS DRUG DISCOVERY (2007)
Drug treatments for obesity: orlistat, sibutramine, and rimonabant
Raj S. Padwal et al.
LANCET (2007)
Combinatorial QSAR modeling of P-glycoprotein substrates
Patricia de Cerqueira Lima et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2006)
Role of metabolism in drug-induced idiosyncratic hepatotoxicity
JL Walgren et al.
CRITICAL REVIEWS IN TOXICOLOGY (2005)
Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States
G Ostapowicz et al.
ANNALS OF INTERNAL MEDICINE (2002)
Concordance of the toxicity of pharmaceuticals in humans and in animals
H Olson et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2000)
Share Paper
