Journal
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
Volume 24, Issue 2, Pages 443-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.hoc.2010.02.004
Keywords
FAB; World Health Organization; IPSS; Myelodysplastic syndromes
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Myelodysplastic syndromes (MDS) are spectrum of bone marrow failure disorders that share a common pathologic feature: cytologic dysplasia. The classification of MDS reflects the understanding of the disease. It is hoped that in the future classification and risk stratification will be based on underlying pathobiology of different disease subsets and molecular signatures where the pathologic classification represents their phenotype. This article reviews MDS classification and risk stratification highlighting differences between the various systems.
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