4.3 Article

Palladium- and Solvent-Free Synthesis of Ynones by Copper(I)-Catalyzed Acylation of Terminal Alkynes with Acyl Chlorides under Aerobic Conditions

Journal

HELVETICA CHIMICA ACTA
Volume 97, Issue 1, Pages 70-75

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/hlca.201300023

Keywords

Ynones; Acyl chlorides; Alkynes; Cross-coupling reactions; Catalysis; Cryptand-22

Funding

  1. K. N. Toosi University of Technology Research Council

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Air-stable Cu-I/cryptand-22complex was found to be a highly active catalyst for the solvent-free cross-coupling reaction of terminal alkynes with different acyl chlorides in the presence of Et3N as base to give the corresponding ynones in quantitative yields.

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