Journal
HELVETICA CHIMICA ACTA
Volume 96, Issue 12, Pages 2191-2195Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/hlca.201200544
Keywords
Nef isocyanide; Thiazolidines; Malononitrile; Isothiocyanates
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An efficient synthesis of alkyl 5-(alkylimino)-3-aryl(alkyl)-2-(dicyanomethylene)-4-hydroxythiazolidine-4-carboxylates, containing polarized CC bonds, via reaction of malononitrile, arylisothiocyanates, and the Nef-isocyanide adducts, under basic conditions, is described.
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