Lanostane Triterpenes from Ceriporia lacerate HS-ZJUT-C13A, a Fungal Endophyte of Huperzia serrata

Two new lanostane triterpenes, 3-acetoxy-15-hydroxylanosta-8,24-dien-21-oic acid (1) and 3-acetoxylanosta-7,9(11),24-trien-21-oic acid (2), along with the four known analogs, 3-6, were isolated from the culture broth of Ceriporia lacerate HS-ZJUT-C13A, a fungal endophyte residing in the stems of the traditional Chinese herb Huperzia serrata. The structures of the new compounds 1 and 2 were established by spectroscopic methods, including UV, IR, HR-ESI-MS, and extensive 1D- and 2D-NMR techniques. To the best of our knowledge, this is the first report on triterpene metabolites from the genus Ceriporia.