Journal
HELVETICA CHIMICA ACTA
Volume 93, Issue 2, Pages 265-271Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/hlca.200900177
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Funding
- NSFC [U0632010]
- Chinese Academy of Sciences [P2008-ZZ08]
- NIH [A1027094]
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R01AI027094] Funding Source: NIH RePORTER
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Three new alpha-tetralone galloylghlcosides, 1-3, were isolated from the fresh pericarps of Juglans sigillata (Juglandaceae), together with six known compounds. The structures of the new compounds were determined as 1,2,3,4-tetrahydro-7-hydroxy-4-oxonaphthalen-1-yl 6-O-[(3,4,5-trihydroxyphenyl)carbonyl]-beta-D-glucopyranoside (1), (IS)-1,2,3,4-tetrahydro-8-hydroxy-4-oxonaphthalen-1-yl 6-O-[(3,4,5-trihydroxyphenyl)carbonyl]-beta-D-glycopyranoside (2), and 1,2,3,4-tetrahydro-7,8-dihydroxy-4-oxonaphthalen-1-yl 6-O-[(3,4,5-trihydroxphenyl)carbonyl]-beta-D-glucopyranoside (3), respectively, on the basis of detailed spectroscopic analyses, and acidic and enzymatic hydrolysis. The antimicrobial activities of the isolated compounds 2, 4, and 7-9 were evaluated.
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