Journal
HELVETICA CHIMICA ACTA
Volume 93, Issue 7, Pages 1369-1374Publisher
WILEY-BLACKWELL
DOI: 10.1002/hlca.200900396
Keywords
-
Categories
Funding
- National Natural Science Funds of China [20772162, 20572136]
- 863 Funds of China [2007AA09Z448, 2006AA09Z422]
- Science Funds of Guangdong Province, China [2007A032600001]
Ask authors/readers for more resources
A new lactone, 1,8-dihydroxy-10-methoxy-3-methyldibenzo[b,e]oxepine-6,11-dione (1), and two new xanthones, 1-hydroxy-8-(hydroxymethyl)-6-methoxy-3-methyl-9H-xanthen-9-one (2) and 1-hydroxy-8-(hydroxymethyl)-3-methoxy-6-methyl-9H-xanthen-9-one (3), were isolated from a mangrove endophytic fungus Phoma sp. SK3RW1M collected from the South China Sea. This is the first report on xanthone derivatives isolated as secondary metabolites from Phoma species. Their structures were elucidated by spectroscopic methods, mainly 1D- and 2D-NMR techniques, and the structure of compound 2 was confirmed by X-ray crystallography. Cytotoxicity assays showed that compounds 1-3 were inactive against KB and KBv200 cells.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available