Recent Developments in Synthetic Chemistry, Chiral Separations, and Applications of Troger's Base Analogues

Troger's base is a well-known chiral molecule with a few unusual structural features. The chemistry of Troger's base analogues has been greatly developed over the last 20 years, and numerous interesting applications in supramolecular chemistry and in molecular recognition have emerged. This Review gives a short overview of the chemistry of Troger's base and its analogues, with particular focus on recent achievements in synthesis, enantiomer separations, and applications.