4.3 Article

Juncenolides H-K, New Briarane Diterpenoids from Junceella juncea

Journal

HELVETICA CHIMICA ACTA
Volume 92, Issue 10, Pages 2092-2100

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/hlca.200900118

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Funding

  1. National Science Council, Taipei [NSC 96-2320-B-110-009]

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Chemical investigation of the Taiwanese gorgonian coral Junceella juncea resulted in the isolation of four new briarane-type diterpenoids, juncenolides H, I, J, and K (1-4). Their structures were determined on the basis of spectroscopic analysis, especially 1- and 213-NMR. The inhibitory effects of compounds 1-4 on superoxide-anion generation and clastase release by human neutrophils were evaluated.

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