4.3 Article

Tuberculariols A-C, New Sesquiterpenes from the Mutant Strain M-741 of Tubercularia sp TF5

Journal

HELVETICA CHIMICA ACTA
Volume 92, Issue 8, Pages 1514-1519

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/hlca.200800451

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Funding

  1. National Science Fund for Distinguished Young Scholars [30325044]
  2. Chinese Ministry of Education [306010]

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Three new sesquiterpenes, tuberculariols A-C(1-3, resp.), were isolated from the mutant strain M-741 of Tubercularia sp. TF 5, an endophytic fungus of Taxus mairei. Their structures were elucidated by spectroscopic analyses including 1D- and 2D-NMR experiments, and HR-Q-TOF-MS. Antitumor and antibacterial properties of these compounds were evaluated.

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