4.3 Article

Limonoids from the Twigs and Leaves of Chukrasia tabularis

Journal

HELVETICA CHIMICA ACTA
Volume 91, Issue 12, Pages 2338-2350

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/hlca.200890254

Keywords

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Funding

  1. Key Project of National Natural Science Foundation [30630072]
  2. Shanghai Municipal Scientific Foundation [06DZ22028]

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Seven new limonoids, tabularisins J-P (1-7, resp.), together with eight known compounds, were isolated from the twigs and leaves of Chukrasia tabularis. Their structures were determined primarily by spectroscopic methods. The potassium channel blocking activities of some of these isolates were evaluated, and a few of them exerted significant activities on the delayed rectifier (I-K) K+ current.

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