Two new dammarane-type bisdesmosides from the fruit pedicels of Panax notoginseng

Two new dammarane-type triterpenoidal saponins, notoginsenosides FP1 (1) and FP2 (2), were isolated from the fruit pedicels of Panax notoginseng, along with 22 known compounds. Their structures were elucidated on the basis of spectroscopic evidences and chemical methods. The known compounds were identified as ginsenosides Rg(1) (3), Re (4), Rb-3 (5), Re (6), Rd (7), Rb-2 (8), Rb-1 (9), F-2 (10), and F-1 (11); as notoginsenosides R-1 (12), Fa (13), and Fc (14); as vina-ginsenoside R-7 (15); as gypenosides IX (16), XVII (17), and XIII (18), and as chikusetsusaponin-L-5 (19), quercetin 3-O-beta-D-glucopyranosyl-(1 -> 2)-beta-D-galactopyranoside (20), kaempferol 3-O-beta-D-glucopyranosyl-(1 -> 2)-beta-D-galactopyranoside (21), benzyl-beta-primeveroside (22), (S)-tryptophan (23), and icariside B-6 (24). Compounds 15, 19 and 22-24 are reported for the first time from the title plant.