4.3 Article

Preparation of two diastereoisomeric decalin synthons and (-)-ambrox

Journal

HELVETICA CHIMICA ACTA
Volume 91, Issue 4, Pages 734-740

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/hlca.200890074

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Two diastereoisomeric decalins, (2S,4aS,5S,6R)- and (2S,4aS,5R,6R)-5-(2-hydroxyethyl)-1,1,4a,6-tetramethyldecalin-2,6-diol (5 and 6) were prepared from the degradation products of oleanolic acid. Starting from 6, (-)-ambrox (4) was synthesized.

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