4.5 Review

Next generation sequencing for clinical diagnostics and personalised medicine: implications for the next generation cardiologist

Journal

HEART
Volume 98, Issue 4, Pages 276-281

Publisher

B M J PUBLISHING GROUP
DOI: 10.1136/heartjnl-2011-300742

Keywords

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Funding

  1. Wellcome Trust
  2. Medical Research Council
  3. National Institute for Health Research
  4. British Heart Foundation
  5. Fondation Leducq
  6. MRC [MC_U120085815] Funding Source: UKRI
  7. British Heart Foundation [SP/10/10/28431] Funding Source: researchfish
  8. Medical Research Council [MC_U120085815] Funding Source: researchfish
  9. National Institute for Health Research [ACF-2007-21-004] Funding Source: researchfish

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The fast moving field of genomic medicine is already impacting on clinical care and cardiologists are fortunate to be in a position to benefit early from the transformative advances in genomics. However, the challenges associated with genomics in the clinic in general, and with next generation sequencing technologies in particular, are significant and cardiologists need to be prepared if they wish to surf the wave of genomic opportunity. This paper presents an overview of the implications of next generation sequencing for clinical diagnostics and personalised medicine in the cardiology clinic.

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