Journal
HEARING RESEARCH
Volume 288, Issue 1-2, Pages 89-99Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.heares.2011.12.003
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Funding
- NIDCD [DC004568, DC000039-15]
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Hereditary deafness is genetically heterogeneous such that mutations of many different genes can cause hearing loss. This review focuses on the evidence and implications that several of these deafness genes encode actin-interacting proteins or actin itself. There is a growing appreciation of the contribution of the actin interactome in stereocilia development, maintenance, mechanotransduction and malfunction of the auditory system. Published by Elsevier B.V.
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