Journal
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
Volume 35, Issue 4, Pages 541-547Publisher
WILEY
DOI: 10.1002/hed.22985
Keywords
ultrasound; thyroid neoplasm; interobserver variability; tumor size; thyroid
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Background The Thyroid Imaging Reporting and Data System (TI-RADS) was proposed based on a scheme similar to Breast Imaging Reporting and Data System (BI-RADS) lexicon used in breast lesions. The purpose of this study was to evaluate its interobserver variability and accuracy. Methods We included 498 nodules in 437 patients undergoing thyroidectomy. Two endocrine surgeons and 2 endocrinologists independently reviewed sonographic images. Results There was moderate to substantial interobserver agreement for final assessment category (kappa = 0.61). The overall sensitivity, specificity, and negative predictive value (NPV) were 94%, 43%, and 96%, respectively. Positive predictive values (PPVs) for categories 4 and 5 were 32% and 60%. The sensitivity was 92%, 99%, 96%, and 89%, whereas the specificity was 25%, 37%, 41%, and 62% for tumor sizes of <2, 2 to 3, 3 to 4, and >4 cm, respectively. Conclusion TI-RADS is a helpful but not optimal reporting tool in characterizing thyroid lesions. Tumor size has a considerable impact on interobserver concordance and diagnostic performance. (c) 2012 Wiley Periodicals, Inc. Head Neck, 2013
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