Journal
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
Volume 32, Issue 11, Pages 1501-1505Publisher
WILEY
DOI: 10.1002/hed.21353
Keywords
parameningeal sarcomas; skull base; pediatric otolaryngology; sinonasal; chemotherapy
Categories
Ask authors/readers for more resources
Background. Nonorbital parameningeal sarcomas are rare, aggressive tumors that arise predominantly in the pediatric population. The purpose of this study was to review their management and to clarify the role of surgery in their treatment. Methods. Treatment, prognostic factors, and outcomes for patients over a 10-year period were reviewed. Results. In all, 34 patients were identified. The most common tumor site was the maxillary sinus, and 73% were rhabdomyosarcoma. Six patients (18%) presented with positive nodal metastases and 3 patients (10%) presented with distant metastases. Overall, 18 patients were treated surgically. Locoregional recurrence rate was 43%; no patients developed distant recurrence. Five-year overall survival was 66.8%, disease-specific survival was 68.1%, and disease-free survival was 31.9%. Conclusions. Pediatric nonorbital parameningeal sarcomas require aggressive multimodality treatment. Although chemo-therapy and radiation constitute the treatment of choice in most cases, surgery may have a role as salvage therapy and in cases that fail to respond to chemoradiation. (C) 2010 Wiley Periodicals, Inc. Head Neck 32: 1501-1505, 2010
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available