Journal
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
Volume 31, Issue 7, Pages 856-866Publisher
WILEY
DOI: 10.1002/hed.21049
Keywords
thyroid nodules; predictive factors for thyroid cancer; predictive index for thyroid malignancy; fine-needle aspiration cytology; follicular neoplasm
Categories
Ask authors/readers for more resources
Background. The objective of this study was to select patients for resection of thyroid malignity among patients with thyroid nodules by integration of predictive indices with fire-needle aspiration cytology (FNAC). Methods. Characteristics of 571 euthyroid patients with thyroid nodules who underwent surgery in our institution were prospectively recorded. Predictive factors for malignancy were identified and categorized as predictive indices that were integrated with FNAC to select patients for surgery. Results. Eighty-three (14.5%) of the 571 patients had thyroid carcinoma. Size >= 4 cm, age >= 65, cervical lymph nodes, solid structure, hypoechogenicity, microcalcification. and elevated serum thyroglobulin levels were independent predictive factors associated with thyroid malignancy. Sensitivity, specificity, and accuracy of FNAC were 88%, 80%, and 81%, respectively, and were 100% for index 3. Conclusions. Patients with malignant and suspicious FNAC findings and, among patients with follicular neoplasm and non-diagnostic FNAC findings, those with >= 2 risk factors should undergo surgery. (C) 2009 Wiley Periodicals, Inc. Head Neck 31: 856-866, 2009
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available