Study of volatile polyacetylenes and terpenoids of Baccharis palustris Heering through GC/MS, GC/HRMS-TOF and GCxGC/HRMS-TOF

Authors

Manuel Minteguiaga¹ , César Catalán² , Eduardo Dellacassa¹ , Elena Stashenko³

1. University of the Republic, Uruguay
2. National University of Tucuman, Argentina
3. Industrial University of Santander, Colombia

Conference / event

II South Brazilian Symposium on Pharmacognosy (II Simpósio Sul-Brasileiro de Farmacognosia), October 2022 (Ponta Grossa, Brazil)

Poster summary

Polyacetylenes are a group of specialized metabolites potentially useful in therapy as antitumorals, being frequent components of the Asteraceae family (especially the Baccharis L. genus). Previously, we studied the unusual composition of B. palustris essential oil (BPEO) from Uruguay, identifying a series of C9-polyacetylenes. Here, we re-analyze this sample conducting several gas chromatography/mass spectrometry protocols with the aim to find new components. Thus, ten oxygenated terpenoids were detected for the first time in BPEO, several of them co-eluting with major components. The polyacetylenes baccharisdyine and the 7-dehydro-baccharisdyine geometric isomers were the main components, while other C9-polyacetylenes were tentatively identified. Applying GCxGC/HRMS-TOF and deconvolution it was possible to identify a lachnophyllum lactone (trace level) of undefined stereochemistry in the second chromatographic dimension. Being B. palustris a highly endangered species, our results might contribute to its preservation as a valuable source of polyacetylenes whose bioactivities need to be studied further.

Keywords

Polyacetylenes, Baccharis palustris, GC/MS, GC/HRMS-TOF, GCxGC/HRMS-TOF, Terpenoids

Research areas

Chemistry, Biological Sciences

References

No data provided

Funding

No data provided

Supplemental files

1. Original publication on B. palustris essential oil (Minteguiaga et al. 2022, Phytochemistry Letters)   Download
2. Scientific publication of the Poster information (Minteguiaga et al. 2023, Braz Arch Biol Technol)   Download

Additional information

Competing interests

No competing interests were disclosed.

Data availability statement

The datasets generated during and / or analyzed during the current study are available from the corresponding author on reasonable request.

Creative Commons license

Copyright © 2024 Minteguiaga et al. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.