Co-exposure to aluminium and cadmium mediates postpartum maternal variation in brain architecture and behaviour

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Authors

Patrick Ichipi-Ifukor¹ , Samuel Asagba¹ , Fidelis Achuba¹

1. Department of Biochemistry, Delta State University, Abraka

Conference / event

20th Neuroscience Soceity of Nigeria Annual Conference, August 2023 (Babcock University Ilesan-Remo, Osun State, Nigeria)

Poster summary

The association between cross-metal exposures of pregnant mothers and postdelivery neuroendocrine functions have remained largely unexplored. This study was carried out to investigate the effect of aluminium chloride (AlCl3) and cadmium chloride (CdCl2) co-exposure on postpartum maternal neuroendocrine and neurometabolic adjustments. Our result is suggestive that maternal exposure to AlCl3 and CdCl2 during pregnancy influenced brain to body weight ratio and increased oxidative stress which may contribute to negative maternal postpartum-behaviours reported.

Keywords

Postpartum behavior, Cadmium, Aluminium, Maternal-adjustment

Research areas

Neuroscience, Pharmacy and Pharmacology, Toxicology

References

No data provided

Funding

No data provided

Supplemental files

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Additional information

Competing interests

No competing interests were disclosed.

Data availability statement

The datasets generated during and / or analyzed during the current study are available from the corresponding author on reasonable request.

Creative Commons license

Copyright © 2023 Ichipi-Ifukor et al. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.