Green synthesis of Solanum xanthocarpum mediated selenium nanoparticles and its biomedical applications

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Authors

Azmathullah Rahmathullah¹

1. Chettinad Academy of Research and Education

Conference / event

International Conference on Current trends on Biomedical Research, September 2022 (Virtual)

Poster summary

Nanoparticles serve to reduce toxicity, enhance bioactivity and improve targeting. Selenium nanopartciles (SeNPs) are explored because of its unique characteristics and various known therapeutic benefits such antimicrobial activity, lower cytotoxic effects, antioxidants activities and reducing risk of cancer, and anti inflammatory activity using albumin denaturation assay. In this study, Solanum xanthocarpum mediated Selenium nanoparticles which has more antimicrobial activity against harmful pathogens and lowered toxic effects and potent anti inflammatory activity and antioxidants activities. Solanum xanthocarpum mediated Selenium nanoparticles were evaluated for its antimicrobial activity and cytotoxic activity using brine shrimp lethality assay. The anti-inflammatory activity is observed using albumin denaturation assay and antioxidant activity evaluated using DPPH assay. These Solanum xanthocarpum stabilized selenium nanoparticle formulations were demonstrated to have biocompatibility, strong potential demonstrated to have biocompatibility, as well as strong potential for application in the fields of medicine and food.

Keywords

Solanum xanthocarpum, Cytotoxicity, Antimicrobial, Nanoparticles, Selenium particles, Anti-inflammatory

Research areas

Pharmacy and Pharmacology, Medicine, Nanoengineering, Genetics

References

No data provided

Funding

No data provided

Supplemental files

No data provided

Additional information

Competing interests

No competing interests were disclosed.

Data availability statement

The datasets generated during and / or analyzed during the current study are available from the corresponding author on reasonable request.

Creative Commons license

Copyright © 2022 Rahmathullah. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.