By analyzing the connection between cruciferous vegetable intake before cancer diagnosis and the survival rate of lung cancer, the researchers showed that the consumption of more cruciferous vegetables prior to the cancer diagnosis increased the life span after the diagnosis by one to two years.
The authors analyzed the impact of eating vegetables, fruits, grains, and high-glycemic-index foods on the risk of developing aggressive prostate cancer, and they found that eating cooked cruciferous greens decreased the risk of prostate cancer.
Researchers from the Weizmann Institute of Science have grown synthetic embryo models of mice outside the womb by starting only with cultured stem cells (i.e. without the use of fertilized eggs).
This innovation enables the growth of tissues and organs for transplantation by using synthetic embryo models and it could bypass the technical and ethical issues involved in the use of natural embryos in research and biotechnology.
Study: 🔗https://doi.org/10.1016/j.cell.2022.07.028🔗
Videos: 🔗https://www.youtube.com/watch?v=dXlEDAGCN7w🔗 and 🔗https://www.youtube.com/watch?v=d0t6NIYGvPI🔗
The clinical trial (single-center, open-labeled trial, 196 patients) suggests that a drug called benzbromarone may be an improved way to treat gout if taken in low dosages: 🔗https://doi.org/10.1002/art.42266🔗
The authors discovered that people with blood types A and B have a greater risk of an embolism from a blood clot than those with type O, and they also suffer less from hypertension.
This randomized controlled trial examined the blood glucose trends of 800 people over one week (measuring responses to 46,898 meals), and the results showed high variability in the glucose response to identical meals. These results suggest that universal dietary recommendations may not benefit everyone.
By investigating 8 participants (male, healthy) during 5 weeks of high-intensity cycling training, the authors uncovered how skeletal muscle adjusts to high-intensity interval training (HIIT), including changes to mechanisms essential for regulating muscular contraction and metabolism.
This systematic review and meta-analysis of 16 studies (76,373 individuals) discovered that individuals with sight issues had a 41% higher risk of cognitive impairment and a 44% higher chance of dementia than individuals without eye issues (i.e. dementia risk in older persons may be increased by vision issues).
This ground-breaking study showed that children’s ability to develop their emotional brain circuits to their full potential is disrupted by unpredictable parental behaviors and an unpredictable environment (e.g. lack of routines and frequent disasters), which makes them more susceptible to mental illness and substance abuse.
The authors investigated 2,680 children (7-10 years old) from 38 schools in Barcelona and discovered that noise levels in the house had no effect on the results of working memory and attention tests but road noise has a negative impact on how well working memory and attention are developed in young children.
Call 2 - 23 MSCA Shaping European Research Leaders for Marine Sustainability (SEAS) postdoctoral research fellow positions at the University of Bergen (Norway) by October 31st, 2022:
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Exercise could allow us to gain control over cravings for unhealthy foods.
The authors discovered that high-intensity exercise can make it easier to resist fatty food (resistance to the phenomenon known as “incubation of craving”), that is, study rats who intensely exercised during a 30-day diet resisted cues for favored and high-fat food pellets.
Na+-taurocholate co-transporting polypeptide (NTCP) is an essential gateway to the liver that enables the recycling of bile acid molecules and it is the cellular receptor of human hepatitis B and D viruses (HBV/HDV), so a better understanding of NTCP could allow the development of liver treatments and to fight HBV and HDV infection.
The authors developed and tested a collection of antibody fragments targeting NTCP by using cryo-electron microscopy – they described two essential NTCP conformations.
The authors discovered that inversions (i.e. a piece of DNA inverting its orientation in the genome) in the human genome are more common than previously thought, which typically lie in regions linked to the development of genomic disorders.
The authors discovered that nanowires move 10 billion electrons per second without any energy loss, which explains the remarkable capacity of ocean-floor bacteria *Geobacter* to send electrons over long distances, and they also found that cooling the environment around the nanowires of these bacteria from room temperature to freezing increases conductivity 300-fold. They concluded that the enhancement of the flow of electricity is enabled by colder temperatures restructuring hydrogen bonds and flattening heme proteins within nanowires. This phenomenon could lead to the development of living and self-repairing electrical circuits, new sources of electricity, and bioremediation strategies.
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