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Gloria Bartolo
United States
Keck Graduate Institute
3
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0
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22
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Article
Commented on
Obesity stigmatisation from obesity researchers
Extremely upsetting to hear. Hope obesity researchers are more aware and cautious of their bias.
Article
Commented on
Obesity: ERAD linked to obesity
Amazing find for age-associated obesity.
Article
Commented on
Obesity Policy Spotlight: Childhood Obesity
How do childhood obesity rates vary across different socioeconomic regions?
Article
Commented on
Structure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agents
It would be amazing to see the efficacy of these drugs in vivo
Article
Commented on
In vitro activity of nitroxoline against clinical isolates of Candida species
This drug can inhibit angiogenesis, gram-negative, gram-positive, biofilms, AND candida species?? What else can it do?!
Article
Commented on
Cathepsin B inhibitors: Further exploration of the nitroxoline core
Amazing work was done on studying the analogs of nitroxoline.
Article
Commented on
Nitroxoline: a broad-spectrum biofilm-eradicating agent against pathogenic bacteria
Wow, amazing finding! Especially if further demonstrated in clinical development.
Article
Commented on
Nitroxoline induces apoptosis and slows glioma growth in vivo
Is nitroxoline given via injections normally, or only approved for oral use in humans?
Article
Commented on
Susceptibility of carbapenemase-producing Enterobacterales (CPE) to nitroxoline
Have preclinical trials started for this drug?
Article
Commented on
Nitroxoline: repurposing its antimicrobial to antitumor application
Are there any specific cancers where nitroxoline is more effective against? Also, has nitroxoline ever reached clinical trials yet?
Article
Commented on
Gas gangrene-associated gliding motility is regulated by the Clostridium perfringens CpAL/VirSR system
Such an amazing link found between gliding, virulence and theCpAL regulatory network. Fascinating!
Article
Commented on
The EngCP endo α-N-acetylgalactosaminidase is a virulence factor involved in Clostridium perfringens gas gangrene infections
In mutant bacterial strains of the EngCP endoα-N-acetylgalactosaminidase, is their virulence attenuated as seen here?
Article
Commented on
Inflammasome Activation Induced by Perfringolysin O of Clostridium perfringens and Its Involvement in the Progression of Gas Gangrene
Are all toxins produced by C. perfringens pore-forming?
Article
Commented on
Combined therapy with gas gangrene antitoxin and recombinant human soluble thrombomodulin for Clostridium perfringens sepsis in a rat model
How often is the antitoxin given as a treatment for gas gamgrene?
Article
Commented on
A Recombinant Probiotic, Lactobacillus casei, Expressing the Clostridium perfringens α-toxoid, as an Orally Vaccine Candidate Against Gas Gangrene and Necrotic Enteritis
Are any GELV vaccines currently approved globally?
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