David Braun, MD, PhD, is an Assistant Professor of Medicine (Medical Oncology) and a member of the Center of Molecular and Cellular Oncology (CMCO) at Yale Cancer Center. Dr. Braun cares for patients with kidney cancers.
How do the metal tolerance and biofilm production capabilities of rhizospheric bacteria compare to those of endophytic bacteria isolated from Robinia pseudoacacia L. in serpentine soils, and what implications do these differences have for biotechnological applications?
The National Climate Resilience Framework is important because it empowers communities to develop tailored solutions to climate challenges, ensuring relevance and effectiveness. By involving local experts and fostering cross-sector partnerships, it integrates diverse expertise and resources, addressing the complex impacts of climate change comprehensively. This approach not only enhances immediate resilience but also promotes long-term sustainability and well-being for communities facing climate-related threats.
Biophysical Journal (BJ) has a mission to publish the highest-quality work that elucidates important biological, chemical, or physical mechanisms and provides quantitative insight into fundamental problems at molecular, cellular, systems, and whole-organism levels. Alongside the goal to publish top-level science, the Biophysical Society (BPS) advocates for next-generation scientists via the Biophysical Journal Postdoctoral Reviewer Program and the BPS Congressional Science & Technology Policy Fellowship Program. Both programs give exceptional career opportunities for mentorship and practical experience to up-and-coming scientists.
Cell Reports Methods is an open access, multidisciplinary journal from Cell Press publishing significant methodological advances of broad utility. Their manuscripts present new methods, toolkits, and empirical studies that inform the use of methods.
Sericin, a hydrophilic protein with a high serine content, ranges from 10 to 400 kDa and is produced in the silkworm's middle silk gland. Its molecular weight, biological activity, and chemical structure vary with the extraction method, influencing its applications. Once discarded by the textile industry, sericin is now being developed in the biomedical field for its beneficial properties, particularly in tissue engineering for burn dressings, drug delivery, bone regeneration, cartilage regeneration, and nerve regeneration.
Each of us is a self-organizing assembly of multiple cell types. From the fertilization of the embryo, our tissue structures develop until we reach adult morphology. At that stage, our ability to self-organize focuses on maintaining this morphology despite daily insults and the aging process. When an injury exceeds our regenerative repair capacity, scar tissue forms as a result.
The development of artificial scaffolds for musculoskeletal applications, particularly in load-bearing situations, necessitates careful consideration of biomechanical aspects to ensure both integrity and function. However, biomechanical loading can also promote tissue formation through mechanotransduction phenomena. Scaffold design can leverage this intrinsic mechanical loading to enhance tissue regeneration.
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